Insulin receptor-related receptor in rat islets of Langerhans
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چکیده
منابع مشابه
Insulin receptor-related receptor in rat islets of Langerhans.
The physiological aspects and roles of the insulin receptor-related receptor (IRR), a novel member of the insulin receptor family, are unknown. Published work shows a characteristic localization of IRR mRNA at the cellular level in the kidney, stomach and brain. In our previous study, a specific antibody against the rat IRR beta subunit was generated and used to identify the IRR-expressing cell...
متن کاملMONOPHASIC STATE OF INSULIN SECRETION IN ISOLATED RAT ISLETS OF LANGERHANS BY K+, Ca2+ AND GLUCOSE
Isolation of rat islets of Langerhans was carried out by using collagenase and the destruction of exocrine tissue was performed through the injection of Hanks' solution into the common bile duct. The identification of the islets was done by techniques including the use of a stereomicroscope against a black background. Vital staining was done by an injection of neutral red solution through t...
متن کاملmonophasic state of insulin secretion in isolated rat islets of langerhans by k+, ca2+ and glucose
isolation of rat islets of langerhans was carried out by using collagenase and the destruction of exocrine tissue was performed through the injection of hanks' solution into the common bile duct. the identification of the islets was done by techniques including the use of a stereomicroscope against a black background. vital staining was done by an injection of neutral red solution through ...
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متن کاملAdventures with insulin in the islets of Langerhans.
Insulin is a small but beautifully organized protein with a unique two-chain structure, the first protein to be sequenced. The mechanism of its biosynthesis invited much initial speculation but was finally clarified by the discovery of proinsulin, its single-chain precursor. The rich present-day field of protein precursor processing via post-translational proteolysis within the secretory pathwa...
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ژورنال
عنوان ژورنال: European Journal of Endocrinology
سال: 1998
ISSN: 0804-4643,1479-683X
DOI: 10.1530/eje.0.1390244